1Greatest relative sensitivity Sr over the 26 uptakes and the three characteristics as given by eq. (60) in the Methods section with ξ = 10−2. 2Uptake log10U at which Sr was found (from U = 10−4.75 µM
Data folder contains 3 files, 1 a model file which defines the functions and parameters used within the model. The second file is the Matlab script to run the model and a 3rd file contains experiment
In multicellular organisms, secreted ligands selectively activate, or "address," specific target cell populations to control cell fate decision-making and other processes. Key cell-cell communication
Cells reliably sense environmental changes despite internal and external fluctuations, but the mechanisms underlying robustness remain unclear. We analyzed how fluctuations in signaling protein concen