Promoter evolution in HIV-1C establishes latent reservoirs highly resistant to reversal

NIAID Data Ecosystem2026-05-10 收录

HIV潜伏库机制

痘病毒转录调控

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https://www.ncbi.nlm.nih.gov/sra/SRP682766 数据链接链接失效反馈

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The study analyses the prevalence and activation properties of novel promotor variants harboring Transcription Factor Binding Site in the HIV1-C Long Terminal Repeat .

创建时间：

2026-03-11

Human cytomegalovirus IE2 both activates and represses initiation and modulates elongation in a context-dependent manner

痘病毒转录调控

巨细胞病毒

Using PRO-Seq, which profiles nascent transcripts, and a recently developed DFF-ChIP approach that informs on local chromatin environment, we show that IE2 controls viral gene transcription in three d

NIAID Data Ecosystem60

Supporting data for “The function of chromatin architectural protein CTCF in HBV transcription"

痘病毒转录调控

染色质功能分析

CTCF is a multiple functional protein in regulating the gene expression, and the dataset shows the effects of CTCF on HBV the transcriptions. The dataset includes the gain-of-function experiments, the

DataCite Commons2021-12-21 更新40

Herpes Simplex Virus 1 ICP22 Inhibits the Transcription of Viral Gene Promoters by Binding to and Blocking the Recruitment of P-TEFb

痘病毒转录调控

疱疹病毒分子生物学

ICP22 is a multifunctional herpes simplex virus 1 (HSV-1) immediate early protein that functions as a general repressor of a subset of cellular and viral promoters in transient expression systems. Alt

Figshare2016-01-19 更新30

ChIP-seq analysis with an antibody directed against the human SMC1 protein in Raji cells (Genbank: KF717093.1) prior to and post induction of BZLF1. ChIP-seq analysis with an antibody directed against the human SMC1 protein in Raji cells (Genbank: KF717093.1) prior to and post induction of BZLF1

EBV宿主互作

痘病毒转录调控

Peaks were identified in both the human and viral (EBV (Human Herpesvirus 4; GenBank accession KF717093.1) genome.

NIAID Data Ecosystem40

Simian Virus 40 Large T Antigen Interacts with Human TFIIB-Related Factor and Small Nuclear RNA-Activating Protein Complex for Transcriptional Activation of TATA-Containing Polymerase III Promoters

痘病毒转录调控

RNA聚合酶启动子

The TATA-binding protein (TBP) is common to the basal transcription factors of all three RNA polymerases, being associated with polymerase-specific TBP-associated factors (TAFs). Simian virus 40 large

PubMed Central30

Promoter evolution in HIV-1C establishes latent reservoirs highly resistant to reversal

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