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资源简介:
FACS dataset for the research article titled "microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function"
应用场景:
创建时间:
2021-12-19
相关数据集
Suppressor activity of Treg in R0 and R cultures a .
aThe data are means±SD of percent suppression measured in co-cultures of proliferating autologous responder cells with Treg generated in R0 or R cultures. R cultures were set up with 1 nM RAPA. Respon
NIAID Data Ecosystem60
Impact of Tcf1/Lef1 deficiency on Treg cells. Impact of Tcf1/Lef1 deficiency on Treg cells
Comparison of transcriptome between control and Tcf1/Lef1-deficient Treg cells Overall design: Splenocytes were harvested from Foxp3-Cre+, Tcf1/Lef1 wild-type or double floxed mice (male and at 16 wee
NIAID Data Ecosystem60
FOXP3-mediated inhibition of a global gene regulator is required for maintaining Treg cell commitment. Homo sapiens
Regulatory T (Treg) cells are characterized by the forkhead transcription factor FOXP3. Mutations in FOXP3 cause autoimmunity in mice and humans. Here, Treg cells as well as conventional T cells were
NIAID Data Ecosystem30
Selective miRNA disruption in Tregs leads to uncontrolled autoimmunity . Mus musculus
A new Treg-specific, FoxP3-GFP-hCre BAC transgenic was crossed to a conditional Dicer knock-out mouse strain to analyze the role of microRNAs (miRNA) in the development and function of regulatory T ce
NIAID Data Ecosystem60
c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes hostâmicrobiota homeostasis
Foxp3+ regulatory T (Treg) cells are essential for immunological tolerance and homeostasis. In peripheral tissues, Treg cells acquire enhanced suppressive functions and co-opt distinct transcriptional
NIAID Data Ecosystem40



