Additional file 6: of PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia

Table S5. GSEA of PU.1 regulated genes. In attempt to identify additional pathways modified by PU.1 silencing in primary human microglia, functionally enriched GO and KEGG gene sets were identified using Gene Set Enrichment Analysis (GSEA) [78, 79] as implemented in WebGestalt [80–82]. The identified pathways (Biological Processes, Molecular Functions, Cellular components, and KEGG analysis) were largely similar to those observed by Fisher’s overrepresentation analysis (Fig. 3b-d), suggesting the significance of PU.1 in the regulation of these functions. (XLSX 28 kb)