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T. b. gambiense type I Mongo gRNA alignments

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Figshare2024-10-05 更新2026-04-28 收录
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We used the predicted fully edited mRNA sequences to identify gRNA genes in the 121 T. b. gambiense type I Mongo minicircles.Alignment allowing no gaps between gRNA and edited mRNA identified two maxicircle-encoded gRNA genes and 532 candidate minicircle-encoded gRNA genes. The vast majority of gRNA genes (523 or 98.7%) are located in 323 cassettes flanked by the 18-bp inverted repeats reported before in T. brucei and T. congolense

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2024-10-05
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