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Iodine(III)-Mediated Selective Intermolecular C–H Amination for the Chemical Diversification of Tryptamines

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Figshare2016-08-01 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Iodine_III_-Mediated_Selective_Intermolecular_C_H_Amination_for_the_Chemical_Diversification_of_Tryptamines/3492986
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Defined hypervalent iodine reagents of the general structure PhI­[N­(SO2R)­(SO2R′)]2 promote the selective direct C–H-amination of the indole core of various tryptamines. Starting from a general C2-amination strategy, subsequent transformations enable a variety of site-selective functionalizations, which proceed with noteworthy high chemoselectivity and provide an overall access to structurally diversified products.
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2016-08-01
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