Crystal structure of human PDK2 complexed with GM10030

Crystal structure of human PDK2 complexed with GM10030 Descriptor: 4-[[[4-[3,5-bis(fluoranyl)-4-(4-oxidanyl-4-oxidanylidene-butoxy)phenyl]-5-[5-chloranyl-2,4-bis(oxidanyl)phenyl]-1,2-oxazol-3-yl]carbonylamino]methyl]benzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Kang, J, Kim, J. Deposit date: 2019-12-12 Release date: 2020-09-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Structural basis for the inhibition of PDK2 by novel ATP- and lipoyl-binding site targeting compounds. Biochem.Biophys.Res.Commun., 527, 2020人源丙酮酸脱氢酶激酶2（PDK2）与GM10030复合物的晶体结构 描述符：4-[[[4-[3,5-二氟-4-(4-羟基-4-氧代丁氧基)苯基]-5-[5-氯-2,4-二羟基苯基]-1,2-噁唑-3-基]甲酰胺基]甲基]苯甲酸、二(羟乙基)醚、甘油…… 作者：Kang J、Kim J。沉积日期：2019-12-12；发布日期：2020-09-30；最后修改日期：2023-11-22。实验方法：X射线衍射（分辨率2.67埃）。引用文献：靶向ATP结合位点与脂酰结合位点的新型化合物抑制PDK2的结构基础，《生物化学与生物物理研究通讯》，527卷，2020年