Neurofibromatosis type 1 (NF1) is the most common tumor predisposition disorder affecting 1/3500 worldwide. Patients are at risk of developing benign (neurofibromas) and malignant peripheral nerve she
The aim of the study is to describe clinical and molecular features characteristic for sporadic and familiar cases with SNF and to also attempt comparisons between the SNF phenotype and classical NF1
Case report of gastrointestinal stromal tumor (GIST) in black african patient with neurofibromatosis type 1. Images of clinical diagnostic, histology and immunochemistry of intestinal nodules showing
Malignant peripheral nerve sheath tumors (MPNST) are aggressive soft-tissue sarcomas which lack effective drugs. Loss of the RAS GTPase-activating protein NF1 and subsequent overactivation of mitogen-
