Crystal structure of 3-O-Sulfotransferase isoform 3 in complex with 8mer oligosaccharide with 6S sulfation

Protein Data Bank Japan2024-10-30 更新2026-03-21 收录

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Crystal structure of 3-O-Sulfotransferase isoform 3 in complex with 8mer oligosaccharide with 6S sulfation Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ... Authors: Pedersen, L.C, Liu, J, Wander, R. Deposit date: 2020-06-26 Release date: 2021-06-23 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Deciphering the substrate recognition mechanisms of the heparan sulfate 3- O -sulfotransferase-3. Rsc Chem Biol, 2, 2021

结合6S硫酸化8聚体寡糖的3-O-磺基转移酶同工型3（3-O-Sulfotransferase isoform 3）的晶体结构配体组成描述：1,2-乙二醇、2-乙酰胺基-2-脱氧-6-O-磺基-α-D-吡喃葡萄糖-(1→4)-β-D-吡喃葡萄糖醛酸-(1→4)-2-脱氧-6-O-磺基-2-(磺酰胺基)-α-D-吡喃葡萄糖-(1→4)-2-O-磺基-α-L-吡喃艾杜糖醛酸-(1→4)-2-脱氧-6-O-磺基-2-(磺酰胺基)-α-D-吡喃葡萄糖-(1→4)-2-O-磺基-α-L-吡喃艾杜糖醛酸-(1→4)-2-脱氧-6-O-磺基-2-(磺酰胺基)-α-D-吡喃葡萄糖-(1→4)-β-D-吡喃葡萄糖醛酸、2-脱氧-6-O-磺基-2-(磺酰胺基)-α-D-吡喃葡萄糖-(1→4)-2-O-磺基-α-L-吡喃艾杜糖醛酸-(1→4)-2-脱氧-6-O-磺基-2-(磺酰胺基)-α-D-吡喃葡萄糖-(1→4)-2-O-磺基-α-L-吡喃艾杜糖醛酸-(1→4)-2-脱氧-6-O-磺基-2-(磺酰胺基)-α-D-吡喃葡萄糖-(1→4)-β-D-吡喃葡萄糖醛酸…… 作者：Pedersen, L.C.、Liu, J.、Wander, R. 存档日期：2020年6月26日发布日期：2021年6月23日最后修改日期：2024年10月30日检测方法：X射线衍射（分辨率1.55埃）引用文献：《解析硫酸乙酰肝素3-O-磺基转移酶-3的底物识别机制》，发表于《RSC化学生物学》（RSC Chem Biol），第2卷，2021年

创建时间：

2020-06-26