The effect of FOXO3 knockdown and PDHA1 knockdown on PDAC cell line Panc-1

ChEBI2016-09-01 更新2026-07-12 收录

癌基因功能

基因敲低效应

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-66404 数据链接链接失效反馈

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The effect of FOXO3 knockdown and PDHA1 knockdown on PDAC cell line Panc-1

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2016-09-01

Expression data from conditionally immortalized MLL-AF9 and MLL-ENL hematopoietic progenitor cells following loss of MLL-fusion oncogene

癌基因功能

转录靶点识别

Chromosomal translocations encoding the MLL-AF9 and MLL-ENL fusion transcription factors are prevalent in infant acute leukaemia and therapy-related leukaemia. In order to conditionally express the ML

NIAID Data Ecosystem90

Additional file 6: of Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells

癌基因功能

CRISPRi筛选

(Movies). Non-targeting siRNA (movie 1) and siPSMA6 (movie 2) were transfected at 25 nM into PANC-1 cells and images were acquired every 4 h with an IncuCyte Live Cell Analysis System. Non-targeting s

Figshare2019-03-22 更新50

Gene expression in p62/SQSTM1-silenced A549 cells.. Gene expression in p62/SQSTM1-silenced A549 cells.

癌基因功能

转录组分析

We used microarrays to detail the programme of gene expression in control or p62/SQSTM1-silenced A549 cells. Overall design: A549 cells were transfected with control siRNA (si CONTROL) or siRNA target

NIAID Data Ecosystem20

Additional file 9: of Epithelial-mesenchymal transition markers screened in a cell-based model and validated in lung adenocarcinoma

上皮-间质转化标志物

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Table S4. GO cellular components enriched with genes belonging to blue module. (XLSX 10 kb)

NIAID Data Ecosystem80

RNA-seq analysis of ex vivo microtumor models comprising control or Arpc4 knockout (KO) PDAC cells

癌基因功能

基因敲除转录组

The loss of Arpc4 resulted in reduced expression of other Arp2/3 complex components, rendering the Arp2/3 complex nonfunctional. The ex vivo microtumor(3D) models were composed of either control or Ar

NIAID Data Ecosystem30

The effect of FOXO3 knockdown and PDHA1 knockdown on PDAC cell line Panc-1

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