Whole exome sequencing of 62 multiple myeloma patients at diagnosis and progression

Whole exome sequencing (WES) was carried out on 186 DNA samples extracted from CD138+ plasma cells collected from 62 multiple myeloma (MM) patients collected at two time points- one prior to any therapy at diagnosis (Time Point 1= TP1) and second at a follow up time point of disease progression (Time Point 2= TP2). WES was also carried out on paired germline DNA obtained from peripheral blood mononuclear cells for all the patients.