Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide (SGC - Diamond I04-1 fragment screening)

Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide (SGC - Diamond I04-1 fragment screening) Descriptor: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B, N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide Authors: Bradley, A, Pearce, N, Krojer, T, Ng, J, Talon, R, Vollmar, M, Jose, B, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2015-07-21 Release date: 2015-09-09 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with N-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide (SGC - Diamond I04-1 fragment screening) To be published

锌指结构域相邻溴结构域蛋白2B（BAZ2B，bromodomain adjacent to zinc finger domain protein 2B）的溴结构域与N-甲基-2,3-二氢噻吩并[3,4-b][1,4]二恶英-5-甲酰胺（SGC - Diamond I04-1片段筛选）复合物的晶体结构
描述符：1,2-乙二醇、锌指结构域相邻溴结构域蛋白2B、N-甲基-2,3-二氢噻吩并[3,4-b][1,4]二恶英-5-甲酰胺
作者：Bradley, A、Pearce, N、Krojer, T、Ng, J、Talon, R、Vollmar, M、Jose, B、von Delft, F、Bountra, C、Arrowsmith, C.H、Edwards, A、Knapp, S、结构基因组学联盟（SGC，Structural Genomics Consortium）
提交日期：2015-07-21
发布日期：2015-09-09
最后修改日期：2024-05-08
实验方法：X射线衍射（分辨率2.13 Å）
引用信息：锌指结构域相邻溴结构域蛋白2B（BAZ2B）第二溴结构域与N-甲基-2,3-二氢噻吩并[3,4-b][1,4]二恶英-5-甲酰胺复合物的晶体结构（SGC - Diamond I04-1片段筛选），待发表