Chronic test results

Name: Chronic test results
Creator: U.S. Environmental Protection Agency
Published: 2024-09-07T03:26:59+08:00

data.gov2024-09-07 收录

环境毒理学

毒性评估

数据链接：

https://catalog.data.gov/dataset/chronic-test-results 数据链接链接失效反馈

官方服务：

资源简介：

Data used for publication. This dataset is associated with the following publication: Struewing, K., P. Weaver, J. Lazorchak , B. Johnson , D. Funk, and D....

本数据集用于学术出版。该数据集关联以下学术出版物：Struewing, K.、P. Weaver、J. Lazorchak、B. Johnson、D. Funk 及 D.……

提供机构：

U.S. Environmental Protection Agency

Effects of the anti-microbial contaminant triclocarban on the reproductive function and ovarian transcriptome of the fathead minnow (Pimephales promelas). Pimephales promelas

环境毒理学

鱼类内分泌干扰

Triclocarban (TCC) is a widely used antimicrobial agent that is routinely detected in surface waters. The present study was designed to examine TCC’s efficacy and mode of action as a reproductive toxi

NIAID Data Ecosystem30

Chemicals grouped by nuclear receptor activity and lesion progression.

受体筛选

毒性评估

Chemicals assigned to nuclear receptor groups (columns) and lesion progression groups (rows).

Figshare2015-12-02 更新00

Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and α‑Fluoroacrylate Containing IL-17 Inhibitors

IL-17抑制剂药物化学

毒性评估

IL-17, a pro-inflammatory cytokine produced mainly by Th17 cells, is involved in the immune response to fungal and bacterial infections, whereas its aberrant production is associated with autoimmune a

NIAID Data Ecosystem00

Identifying key events from Per- and Polyfluoroalkyl Substances exposure that influence larval zebrafish in light:dark assay using RNA-sequencing analysis of perfluorohexane-1-sulfonate (PFHxS). Identifying key events from Per- and Polyfluoroalkyl Substances exposure that influence larval zebrafish in light:dark assay using RNA-sequencing analysis of perfluorohexane-1-sulfonate (PFHxS)

环境毒理学

转录组学分析

Gene expression data from short-term in vivo studies shows efficacy in quantifying concentration-dependent effects that inform toxicity outcomes, particularly for chemicals with limited toxicity data

NIAID Data Ecosystem30

Effect of application of intra- or extracellular acyl-CARs on IhERG deactivation time constants.The hERG current was fitted to a two exponential function (see Methods for details).

hERG通道电生理

毒性评估

The values of tau1 and tau2 are given in ms. Values were obtained when the membrane potential returned to −55 mV after stepping to −10 mV for 5s. *p

Figshare2015-12-02 更新00