EURL ECVAM Review of non-animal models in biomedical research - Autoimmune diseases

This highly curated knowledge base contains detailed descriptions of 183 non-animal models and recorded a sharp increase in the number of articles employing them between 2016 and 2018 compared to the 2014-2015 period. The majority of these models are based on the use of cells, particularly primary cells, and certain models are preferentially exploited for certain types of conditions, such as in the case of ex-vivo models like biopsies for skin diseases, and stem cells in the case of type 1 diabetes.