Exploiting Copper Redox for 19F Magnetic Resonance-Based Detection of Cellular Hypoxia
收藏Figshare2016-03-03 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Exploiting_Copper_Redox_for_sup_19_sup_F_Magnetic_Resonance_Based_Detection_of_Cellular_Hypoxia/2885305
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资源简介：
We report a pair of fluorinated, redox-active copper complexes for potential use as 19F MRI contrast agents for detecting cellular hypoxia. Trifluorinated Cu(II) ATSM-F3 displays the appropriate redox potential for selective accumulation in hypoxic cells and a completely quenched 19F NMR signal that is “turned on” following reduction to Cu(I). Incubation of cancer cells with CuATSM-F3 resulted in a selective detection of 19F signal in cells grown under hypoxic conditions.
创建时间：
2016-03-03
