Transcriptional profiling of nutrient-balanced early trilineage differentiations derived from H9 hPSCs.
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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资源简介:
Here, we show unexpected and crucial metabolic nodes through TCA flux and glutaminolysis that modulate germ layer specification. Previous reports have shown that sustained glycolytic flux though MYC regulation is required for ectoderm specification. Our data support the finding that the germ layers have distinct metabolic profiles, but through investigation into the role of OXPHOS in germ layer specification.
提供机构:
UCLA
创建时间:
2022-02-20



