RNA-seq of intestinal epithelia of Candida albicans treated mice

Purpose: To explore the influence of Candida albicans treatment in mice intestinal epithelia. Method: 108 CFU C. albicans or PBS was gavaged to Apoe-/- mice every 3 days for 2 weeks. mRNA profiles were generated by deep sequencing.Results: Several signaling pathways were changed after C. albicans treatment, including response to hypoxia pathway. Overall design: Expression profiling by RNA-seq, profiling of intestinal epithelia after C. albicans treatment.