"该数据集主要为了寻找参与调控AR和GR稳定性的关键成员。利用外界刺激处理前列腺癌细胞系,使得 AR 和 GR 处于不同的稳态,进而通过免疫共沉淀-质谱鉴定的方式,比较不同外界刺激下 AR 或 GR 结合的蛋白质机 器差异,获得通过相互作用直接调控 AR 或 GR 稳态的蛋白质机器组分。数据量11 MB"
Once AKT is localized at the plasma membrane, it is phosphorylated at two critical residues for its full activation. These residues are a threonine (T308 in AKT1) in the activation loop within the cat
Structural studies showed that activation of RIPK3 by RIPK1 involves the formation of a functional hetero-oligomeric amyloidal signaling complex that mediated programmed necrosis (Li J et al. 2012; Mo
DLL3 interacts with NOTCH1 when the two proteins are expressed in the same cell (inferred from mouse homologs). The interaction occurs in endosomes and targets NOTCH1 for degradation in lysosomes befo
A–The growth medium, B–the low-conductivity buffer, C–the hyperosmotic buffer, D–the high-conductivity buffer, E–the buffer with calcium. Values in bold and the symbol next to them emphasize if the ce