Binning results in P21-Nrl-WT vs. P21-Nrl-KO, P0 vs. P21-Nrl-WT and P0 vs. P21-Nrl-KO comparisons. Custom bioinformatics pipeline and binning of P21-Nrl-WT vs. P21-Nrl-KO (S4.1), P0 (P0CE + P0NE) vs.
B, baseline; SC, shock-context; CS, context-shock; t, trisomic (Ts65Dn); c, control; tm, trisomy injected with memantine; cm, control injected with memantine; cs, control injected with saline; sal, sa
aBW – body weight;borgan weights/body weight ratios are given in organ weight[g]*100/body weigh [g].*pSignificant differences in gross phenotype between Cyp51+/− and Cyp51+/+ mice.