ATM gene mutation carriers are predisposed to estrogen receptor (ER)-positive breast cancer (BC). ATM prevents BC oncogenesis by activating p53 in every cell; however, much remains unknown about tissu

NIAID Data Ecosystem50

Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.

乳腺癌分子机制

受体信号通路

Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript

NIAID Data Ecosystem40

Shc proteins in DMBA induced breast cancer

乳腺癌分子机制

基因编辑模型

The principal factors that control mammary tumor formation remain insufficiently defined. Shc adaptor proteins play an important role in signaling by three well-established biological markers for prog

NIAID Data Ecosystem70

The primer sequence.

乳腺癌分子机制

癌症药物靶点

BackgroundBreast cancer continues to be a predominant cause of female mortality globally, characterized by limited therapeutic options and substantial adverse effects. Artesunate (ART), a traditional

Figshare2025-08-04 更新40

Cyclin D1 determines estrogen dependent signaling in human breast cancer cell line MCF7

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