Crystal structure of human carbonic anhydrase II in complex with the inhibitor 4-Pyridin-3-yl-benzenesulfonamide

Crystal structure of human carbonic anhydrase II in complex with the inhibitor 4-Pyridin-3-yl-benzenesulfonamide Descriptor: 4-pyridin-3-ylbenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Ferraroni, M, Supuran, C.T, Scozzafava, A, Carta, F. Deposit date: 2017-02-07 Release date: 2017-12-27 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Sulfonamide carbonic anhydrase inhibitors: Zinc coordination and tail effects influence inhibitory efficacy and selectivity for different isoforms Inorg.Chim.Acta., 470, 2018

人类碳酸酐酶II与抑制剂4-吡啶-3-基苯磺酰胺（4-Pyridin-3-yl-benzenesulfonamide）结合的晶体结构。描述符：4-吡啶-3-基苯磺酰胺、碳酸酐酶2（Carbonic anhydrase 2）、甘油（Glycerol）等。作者：Ferraroni, M、Supuran, C.T、Scozzafava, A、Carta, F。存储日期：2017-02-07；发布日期：2017-12-27；最后修改日期：2024-01-17。实验方法：X射线衍射，分辨率1.4埃（1.4 Å）。引用文献：《磺酰胺类碳酸酐酶抑制剂：锌配位与尾部基团效应影响不同同工型的抑制效力与选择性》，刊载于《无机化学学报》(Inorg.Chim.Acta.) 第470卷，2018年。