Additional file 1 of Comprehensive analysis on subchondral bone marrow lesions of human osteoarthritis by integrating bulk and single-cell transcriptomes

Additional file 1: Supplementary Table S1. Detailed information of nine samples from six donors in present study. Supplementary Table S2. Overlapping differentially expressed genes between two differentially expressed genes list  with similar direction of effect. Supplementary Table S3. GO analysis on differentially expressed genes (n=86 genes) in OA subchondral bone marrow lesion (top 10 dispalyed). Supplementary Table S4. KEGG analysis on differentially expressed genes (n=86 genes) in OA subchondral bone marrow lesion (top 7). Supplementary Table S5. Overlapping differentially expressed genes between four differentially expressed genes  with same expression trend. Supplementary Table S6. Summary of OA risk genes reported in genome-wide association studies. Supplementary Table S7. IL11-TF network prediction. Supplementary Table S8. VCAN-TF network prediction. Supplementary Table S9. Predicted miRNAs binding to IL11 through databases and publisheddatasets  (top 20 displayed). Supplementary Table S10. Predicted miRNAs binding to VCAN through databases and published datasets  (top 20 displayed). Supplementary Table S11. Top 20 predicated lncRNA binding to hsa-miR-424-5p , hsa-miR-670-5p and has-mir-4261 through databases. Supplementary Table S12. The estimated cell proportions of present bulk RNA-seq by MuSiC. Supplementary Table S13. Customized signature matrix of scRNA-seq for MCP counter. Supplementary Table S14. Cellular abundance of present bulk RNA-seq predicted by MCP counter. Supplementary Table S15.Cellular abundance of independent subchondral bone RNA microarray profile(E-MTAB-5564) predicted by MCP counter.