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Mutated RNA component of the telomerase induces apoptosis via GADD45-? in hTERT-overexpressing primary fibroblasts

ChEBI2011-05-28 更新2026-07-21 收录

端粒酶功能突变

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-24975 数据链接链接失效反馈

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Mutated RNA component of the telomerase induces apoptosis via GADD45-? in hTERT-overexpressing primary fibroblasts

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创建时间：

2011-05-28

蛋白质鉴定

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Caspases are a family of enzymes that regulate biological processes such as inflammation and programmed cell death, through proteolysis. For example, in the intrinsic pathway of apoptosis, cell death

NIAID Data Ecosystem90

RETRACTED ARTICLE: A novel Fas-binding outer membrane protein and lipopolysaccharide of Leptospira interrogans induce macrophage apoptosis through the Fas/FasL-caspase-8/-3 pathway

钩端螺旋体致病机制

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Leptospira interrogans is the major causative agent of leptospirosis, an emerging, globally spreading zoonotic infectious disease. The pathogen induces macrophage apoptosis, but the molecular b

Taylor & Francis Group2024-02-08 更新40

Propionibacterium acnes induces intervertebral disc degeneration by promoting nucleus pulposus cell apoptosis via the TLR2/JNK/mitochondrial-mediated pathway

椎间盘退变机制

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Evidence suggests that intervertebral disc degeneration (IVDD) can be induced by Propionibacterium acnes (P. acnes), although the underlying mechanisms are unclear. In this study, we analyzed the path

Figshare2019-04-02 更新20

The molecular consequences of Nix ablation on apoptosis and erythropoiesis. Mus musculus

红细胞生成分子机制

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Normal erythropoiesis requires a critical balance between proapoptotic and antipaoptotic pathways. Bcl-xl, an antiapoptotic protein is induced at end-stages of differentiation of erythroid precursors

NIAID Data Ecosystem90

qPCR expression levels for genes involved in apoptosis.

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基因表达定量

Values are indicative of over-expression of Bax, Caspase-3 and Cyt C and sub-expression of Bcl-2 and Caspase-8 in cells treated with Cas-II gly in agreement with the results of whole genome microarray

Figshare2015-12-02 更新30

Mutated RNA component of the telomerase induces apoptosis via GADD45-? in hTERT-overexpressing primary fibroblasts

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