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Nanopore sequencing of internal 2'-PO4 modifications installed by RNA repair

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NIAID Data Ecosystem2026-03-14 收录
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Ligation by plant and fungal RNA ligases yields an internal 2'-phosphate group on each RNA ligation product. This work allowed us to define several unique signals produced by 2'-phosphorylated RNAs during nanopore sequencing of mRNAs, tRNAs, and synthetic oligonucleotide substrates.

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2022-12-15
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