Reprogram-Seq leverages organ-specific cell atlas data with single-cell perturbation and computational analysis to predict, evaluate, and optimize TF combinations that reprogram a cell type of interes

NIAID Data Ecosystem40

High throughput single-cell whole transcriptome analysis of induced cardiomyocytes during direct cardiac reprogramming [Bulk-seq]

单细胞转录组学

心脏细胞重编程

Direct lineage conversion offers a new strategy for tissue regeneration and disease modeling. Despite recent success in directly reprogramming fibroblasts into a wide spectrum of cell types, the preci

NIAID Data Ecosystem30

TBX20 Consolidates Cardiac Reprogramming Factors to Enhance Contractility and Energy Metabolism in Human Induced Cardiomyocytes [scRNA-Seq]. TBX20 Consolidates Cardiac Reprogramming Factors to Enhance Contractility and Energy Metabolism in Human Induced Cardiomyocytes [scRNA-Seq]

心脏细胞重编程

单细胞转录组学

Background: Direct cardiac reprogramming of fibroblasts into cardiomyocytes has emerged as one of the promising strategies to remuscularize the injured myocardium. Yet, it is still insufficient to gen

NIAID Data Ecosystem40

Identification and Characterization of a Novel Multipotent Sub-Population of Sca-1+ Cardiac Progenitor Cells for Myocardial Regeneration

心脏祖细胞

心肌再生

Methods and ResultsThe cardiac stem/progenitor cells from adult mice were seeded at low density in serum-free medium. The colonies thus obtained were expanded separately and assessed for expression of

Figshare2016-01-18 更新30

Rig1 agonists in fibroblast to cardiomyocyte reprogramming

资源简介：

相关数据集