In the past, the heart muscle was thought to originate from a single source of myocardial progenitor cells. More recently, however, an additional source of myocardial progenitors has been revealed to
Recurrent hypoglycemia is common in infants and children. In developing rat models, recurrent moderate hypoglycemia leads to neuronal injury in the medial prefrontal cortex. To understand the effects
Hotspot gain-of-function mutations in the YEATS domain of the histone reader protein ENL have been identified in Wilms’ tumor. To investigate the pathogenic role of these cancer-associated ENL mutatio
Normal-mutant pairs (8–10) of littermates from 8 litters were analyzed for apoptosis by TUNEL assay and for cell proliferation by phospho-Histone3 immunohistochemistry as described in the Methods sect
