Liver fibrosis is a reversible wound-healing response to liver injury and hepatic stellate cells (HSCs) are central cellular players that mediate hepatic fibrogenesis. However, the molecular mechanism
Renal fibrosis is a hallmark of diabetic nephropathy (DN) and is characterized by an epithelial-to-mesenchymal transition (EMT) program and aberrant glycolysis. The underlying mechanisms of renal fibr
To investigated the role of CD73 in liver fibrosis, RNA-sequencing of fibrotic liver tissues from CCL4-induced mice were performed. Three groups (three mice for each group) were included in this study
Structure of NNQQNY as an insert in T7 endonuclease I Descriptor: Endonuclease I Authors: Guo, Z, Eisenberg, D. Deposit date: 2008-02-19 Release date: 2008-07-22 Last modified: 2023-08-30 Method: X-RA
SCN5A coding for sodium channels in the heart and its reduced activity implicated various biological processes including fibrogenesis. However, the mechanistic interplay between loss of SCN5A activit