Experiment design of steepest ascent and corresponding responsea.
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aX1, lactose; X2, Peptone; X6 , temperature.bzero level in the PB design in Table 1.crange of the unity level.destimated coefficient ratio from Eq. (1).eorigin step unit × slope.fProportion ×1.337, where 1.337 is a factor determined by experimenter based on process knowledge or other practical consideration, and 1.337 is appropriate in this example.
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2015-12-02
