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Effect of Pdk4 smooth muscle cell-specific knockout on atherosclerosis analyzed by scRNAseq

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NIAID Data Ecosystem2026-05-02 收录
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Knockout of Pdk4 in smooth muscle cells dramatically decreased inflammation, and increased gene expressions in TGFb signaling and glycolysis in the aorta. Pdk4 was knocked out at age of 4-6 wk, followed high fat diet feeding for 4 months. Fresh whole aorta were digested for scRNAseq.

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2025-09-01
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