Sestrins regulate age-induced deterioration of muscle stem cell homeostasis [RNA-seq]
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
We utilize RNA-Seq to evaluate how loss of Sestrin1,2, a conserved set of stress-inducible proteins, alters the metabolism and quiescent state of young (2-3 months) Muscle Stem Cells (MuSCs) during the regenerative response. Overall design: Bulk RNA-Seq at 0, 7, and 21 days post-injury for both wild-type (WT) and Sestrin1,2 knockout (SKO) MuSCs. 2 replicates are provided per condition at each timepoint.
创建时间：
2021-10-07
