Targeting ALK fusion-specific super enhancer to suppress growth of non-small cell lung cancer cells in vitro and in vivo
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资源简介：
This study is the first to elucidate the 3D genomic regulatory mechanism of the EML4-ALK fusion gene. Targeting transcriptional expression of this fusion gene may provide a novel precision therapy that bypasses the kinase mutation-induced drug resistance in NSCLC.
提供机构：
Jilin University创建时间：
2025-11-01
