Current screening methods for ovarian cancer (OC) have failed to demonstrate a significant reduction in mortality. Uterine lavage for the collection of disseminated cancer cells combined with TP53 ult
Abstract Fragmentomic features of circulating cell free mitochondrial DNA (ccf-mtDNA) including fragmentation profile, 5' end base preference and motif diversity are poorly understood. Here, we genera
The protein cargoes of tumor-derived extracellular vesicles (TEVs) are promising biomarkers for cancer diagnosis, yet their application is constrained by EV heterogeneity and complex assay procedures.
BackgroundWe prospectively investigated the potential of tumor-informed circulating tumor DNA (ctDNA) for detecting minimal residual disease (MRD) in surgically resected biliary tract cancer (BTC).Met
