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Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB signaling in triple negative breast cancer [ChIP-Seq]

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE155684
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The purpose of this study was to elucidate the effects of ERβ on the genomic distribution of NFκB and RNA Polymerase II phospho-Ser2, as well as changes in H3K27me3, H3K27ac, in MDA-MB-231 triple negative breast cancer cells. ERβ-expressing MDA-MB-231 cells were treated with ethanol vehicle or 1nM E2 for 5 days, followed by 30 minutes of 20ng/ml TNFα in replicates of 2.
创建时间:
2022-03-09
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