Synthesis of C-3‘ Methyl Taxotere (Docetaxel)
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Protected (3R,4S)-N-Boc-3-hydroxy-4-methyl-4-phenylazetidin-2-one has been synthesized stereoselectively and used to esterify protected 10-desacetylbaccatin III to give, following removal of the protecting groups, novel C-3‘ methyl taxotere (docetaxel).
创建时间:
2016-08-19




