Longitudinal associations between change in sedentary behaviors over 6 years and cognitive function after removing participants with the lowest cognitive performance scores (eg, below the education level-specific tenth percentile) (N = 2,321)a.

T2, T3: tertile of change in time spent in each of the sedentary behaviors.Tertile 1 used as reference.aValues are mean difference (95% confidence interval) in cognitive scores, lowest category as reference.bP for trend across categories.cmodel a (crude): interval between first sedentary behavior assessment and cognitive evaluation.dmodel b: model a + age, gender, supplementation group, education, occupational categories, time-dependent retirement status + baseline value.emodel c: model b + tobacco use status, BMI, CES-D score, general health status, history of cardiovascular diseases, diabetes and hypertension.fmodel d: model c + delta of leisure-time physical activity, delta of remaining sedentary behaviors.