Figure S1 - A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 Phenotype
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Effect of the CDKN1B 5′UTR in HEK293 and SH-SY5Y cell lines. The wild type 5′UTR of the CDKN1B gene, but not the c.-456_-453delCCTT containing one, is able to induce luciferase activity in asynchronous SH-SY5Y (A) and HEK293 (B) cell lines. On the right side of each panel the flow cytometry evaluation of the corresponding cell line is shown. Data represent three independent experiments. P-values were calculated using a two-tailed t-test. *p (PDF)
创建时间:
2015-12-02



