Chromatin accessibility of ex vivo derived Be-g2 cells

Naive B cells cultured in the presence of IL-2 and IFN-g (Be-g2) leads to a distinct programming outcome. To determine the epigenetic programming changes during Be-g2 differentiation ATAC-seq was performed on Be-0, Be-IL2, Be-IFNg, and Be-g2 cells. These data define the chromatin accessibility landscape of Be-g2 cells and the changes that occur during thier differentiation. Overall design: Be-0, Be-IFNg, Be-IL2, Be-IFNg, and Be-g2 cells were analyzed by ATAC-seq.