Main characteristics of studies included in the meta-analysis.

SOC: source of controls; PB: population-based. MAF: minor allele frequency. HWE: Hardy-Weinberg equilibrium; Y: yes; N: no; NE: not estimate. TIA: transient ischemic attack; ICVD: ischemic cerebrovascular disease. SVO: small-vessel occlusion; LAA: large-artery atherosclerosis; CE: cardioembolism; SUE: stroke of undetermined etiology. CT: computed tomography; MRI: magnetic resonance imaging.