Dissociation constants (KD) for gp120 binding to Siglec Receptors.
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1The strain abbreviations with Genbank accession numbers in parenthesis are: UG037 for 93UG037 (U51190), PBJ for SIVsmm PBj1.9 (M31325), US715 for 92US715 (U04919), UG21 for 92UG21-9 (U08804), NL4-3 (M38432), MW959 for 93MW959 (Clade C, U08453).2The trimeric gp120 is from the 93UG037 strain. The recombinant protein was expressed in CHO cells fused with a trimerization domain from T4 bacteriophage fibritin [51], [52].3ND: Not Done.4The symbols for polyacrylamide (PAA)-conjugated model carbohydrates are 3′SL, 6′SL, and 8′SA for α(2,3)-sialyllactose-PAA, α(2,6)-sialyllactose-PAA, and Neu5Acα(α2,8)-Neu5Acα(α2,8)Neu5Acα-sp-PAA, respectively.
创建时间:
2015-12-02



