"COMPARATIVE STUDY OF TREATMENT ADHERENCE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS BY TERRITORIAL DISTRIBUTION AND ITS IMPROVEMENT (A CASE STUDY OF ANDIJAN REGION)"

This thesis is devoted to the comparative assessment of treatment adherence among patients with type 2 diabetes mellitus in different territorial units of Andijan region and to the identification of possible ways for its improvement. Type 2 diabetes mellitus remains one of the leading chronic diseases requiring continuous treatment, long-term follow-up, and active patient participation in disease control. In this regard, treatment adherence is considered one of the key conditions for achieving stable glycemic control and preventing complications. The thesis analyzes how adherence varies depending on territorial living conditions, accessibility of healthcare services, educational level, family support, and clinical characteristics of patients. The study is based on a comparative regional approach and examines the differences in medication intake, dietary compliance, regularity of follow-up visits, and overall treatment behavior among patients living in urban and rural areas of Andijan region. The results of the thesis showed that adherence indicators were relatively higher in territories with better healthcare access, while patients from remote and rural districts demonstrated lower adherence levels. Poor adherence was more often associated with limited medical supervision, low health awareness, insufficient social support, and longer duration of disease. The thesis also emphasizes that treatment adherence should be viewed not only as an individual patient behavior but also as a reflection of organizational and territorial conditions of healthcare delivery. The obtained findings support the need for region-specific interventions aimed at improving diabetes education, strengthening follow-up systems, increasing access to healthcare services in rural areas, and encouraging family participation in treatment support. The practical significance of this thesis lies in its potential use for improving regional strategies for the management of patients with type 2 diabetes mellitus and reducing the burden of diabetes-related complications.