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Effect of masitinib on the activity of protein kinases.

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https://figshare.com/articles/dataset/_Effect_of_masitinib_on_the_activity_of_protein_kinases_/552785
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Recombinant tyrosine kinase assays were performed using an ELISA-based assay with poly(Glu,Tyr, 4∶1) as the substrate. All protein kinases were human versions except where noted. Cell-based assays were performed using Ba/F3 cells expressing the various enzymes, and cell proliferation was assessed using WST-1. All concentrations were tested in duplicate (recombinant assays) or triplicate (cell-based assays). Results are the means±standard deviations from at least three independent experiments except where noted. *Results are from a single experiment performed as part of a kinase screen by Proqinase (Germany).
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2009-09-30
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