Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4

Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... Authors: Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. Deposit date: 2018-09-30 Release date: 2018-11-28 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (7.14 Å) Cite: Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018

本数据集对应处于“2-节状不对称”构象的双异聚体N-甲基-D-天冬氨酸（NMDA）受体GluN1/GluN2A，该受体与甘氨酸、谷氨酸结合，体系中含有1微摩尔浓度的氯化锌，且pH值为7.4。
描述符：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、离子型谷氨酸受体……
作者：Jalali-Yazdi F、Chowdhury S、Yoshioka C、Gouaux E
提交日期：2018-09-30
发布日期：2018-11-28
最后修改日期：2024-11-06
测试方法：电子显微镜（分辨率7.14埃）
引用文献：《GluN1/GluN2A型NMDA受体的锌与质子抑制机制》，《细胞》，175卷，2018年