Metabolic Effect of Fluid Resuscitation in HS-65BV+VP.

Numbers in brackets indicate when the sample size decreased from the initial twelve animals. Values are mean ± SD. BW, blood withdrawal; HS, hemorrhagic shock; NS, normal saline; BR, blood reinfusion; VO2/DO2, oxygen consumption divided by oxygen delivery. The data was analyzed using two-way repeated measures ANOVA. There were overall statistically significant interactions between treatment and time for aortic pH (p = 0.043), aortic O2 content (p≤0.001), and VO2/DO2 ratio (p≤0.001). There was no overall statistically significant treatment effect. *p≤0.05 and ‡p≤0.001 denote statistically significant differences between groups at the specified time point. ap≤0.05 and cp≤0.001 denote statistically significant differences vs baseline using the Holm-Sidak test for multiple comparisons showing the differences only when they occurred in one of the two groups.Metabolic Effect of Fluid Resuscitation in HS-65BV+VP.