Mus musculus breed:Balb/c Transcriptome or Gene expression. Mus musculus breed:Balb/c

Study goals:To understand the impact of sustained lymph node retention of exosomes on whole lymph node gene expression and function.Relevance: Exosomes have a multitude of effects in immunomodulation and cancer cells secrete exosomes that alter the fate of cancer progression. In this study we seek to: 1) understand the effect of TLR stimulation on local cells producing exosomes 2) understand the impact of cancer secreted exosomes on cancer progression.