BindingDB Entry 50038562: Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.

Small molecule binding data for protein 5'-AMP-activated protein kinase catalytic subunit alpha-1, ALK tyrosine kinase receptor, AXL receptor tyrosine kinase, Aurora kinase A-interacting protein, Aurora kinase B/Inner centromere protein, BMP-2-inducible protein kinase, CAMK2A, CDK7/Cyclin H/MNAT1, CaM kinase II, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2-associated protein 2, Death-associated protein kinase 2, Death-associated protein kinase 3, Dual specificity protein kinase CLK2, Dual specificity protein kinase CLK4, Dual specificity protein kinase TTK, Dual specificty protein kinase CLK1, EPHB1, Ephrin receptor, Ephrin type-A receptor 3 (EPHA3), Ephrin type-B receptor 4 (EphB4), Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Epithelial discoidin domain-containing receptor 1, Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Glycogen synthase kinase-3, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, JAK2/TYK2, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Lysyl-tRNA synthetase, MAP kinase p38, MAP kinase-activated protein kinase 2, MAP kinase-activated protein kinase 3, Macrophage colony stimulating factor receptor, Macrophage-stimulating protein receptor, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase kinase kinase kinase 5, NT-3 growth factor receptor, Neurotrophic tyrosine kinase receptor, Neurotrophic tyrosine kinase receptor type 2, Phosphorylase kinase, Platelet-derived growth factor receptor, Platelet-derived growth factor receptor beta, Protein kinase N2, RAF serine/threonine protein kinase, Receptor tyrosine-protein kinase erbB-4 (HER4), Ribosomal protein S6 kinase (P70S6K), Ribosomal protein S6 kinase alpha 2, Ribosomal protein S6 kinase alpha 3, Ribosomal protein S6 kinase alpha 5, SRC, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 17A, Serine/threonine-protein kinase 17B (STK17B), Serine/threonine-protein kinase 2, Serine/threonine-protein kinase 4 (STK4), Serine/threonine-protein kinase AKT, Serine/threonine-protein kinase Aurora-C, Serine/threonine-protein kinase D1, Serine/threonine-protein kinase GAK, Serine/threonine-protein kinase Nek2, Serine/threonine-protein kinase PCTAIRE-1, Serine/threonine-protein kinase PLK4, Serine/threonine-protein kinase c-TAK1, TRAF2 and NCK-interacting protein kinase (TNIK), Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BMX, Tyrosine-protein kinase BTK, Tyrosine-protein kinase CSK, Tyrosine-protein kinase Fes/Fps, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase STK16 (STK16), Tyrosine-protein kinase Yes, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor FLT3, Tyrosine-protein kinase receptor TYRO3, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), and myosin light chain kinase 2, Uniprot L7RSL3, O00444, O14976, O43293, O75582, O75716, O75956, O94768, O94804, P00519, P00533, P04626, P04629, P06213, P06239, P06241, P06493, P07332, P07333, P07947, P07948, P07949, P08069, P08581, P09619, P09769, P10721, P11362, P12931, P15056, P15735, P16234, P17948, P21802, P22607, P23443, P23458, P27448, P29320, P29322, P29323, P29597, P30530, P31751, P33981, P35916, P35968, P36888, P41240, P42685, P43403, P49137, P49759, P49760, P49841, P50613, P51812, P51813, P51955, P54756, P54760, P54762, Q00536, Q02763, Q04912, Q05397, Q06187, Q06418, Q08345, Q13043, Q13131, Q13555, Q15046, Q15139, Q15303, Q15349, Q15759, Q16288, Q16513, Q16539, Q16620, Q16644, Q16816, Q541P7, Q96GD4, Q9H1R3, Q9H2G2, Q9HAZ1, Q9NSY1, Q9NWT8, Q9UEE5, Q9UF33, Q9UIK4, Q9UKE5, Q9UM73, Q9UQB9, and Q9UQM7