Association between long-acting insulin use and cancer for new users by dose category (As-Treated Analysis).

Hazard ratios and their 95% CIs were obtained from Cox proportional hazards models adjusted for gender and age at the start of the dose category.CI, confidence interval; HR, hazard ratio; IR, incidence rate per 100 person-years.Patients were followed until the first occurrence of one of the following events: the patient switched treatments or augmented with another long-acting insulin, the patient developed cancer, death, the study ended, or one year after the patient’s last visit in the database.Only patients with dose data for the insulin treatment that they initiated are included in this analysis.Association between long-acting insulin use and cancer for new users by dose category (As-Treated Analysis).