"Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses." Nathan and Rossin et al

Supplemental Tables S3 and S4 for article titled "Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses." TABLE S3. List of SARS-CoV-2 epitopes tested by HLA class I-peptide stability assay. Each row indicates a highly networked SARS-CoV-2 epitope and columns include the following: HLA, Peptide #, Epitope Code, Epitope Sequence, Gene, Amino Acid, Protein, Protein Region, Network Score, NetMHC Binding Score, HLA Stabilization, 50% Experimental Binder (YES/NO). TABLE S4. Sequences of Highly Networked HLA stabilizing SARS-CoV-2 Epitopes in the B.1.117, B.1.351, P.1 and B.1.617 Variants, Related to Figure 3. Mutations from ancestral strain delineated in bold. Each row indicates a highly networked SARS-CoV-2 epitope and columns include the following: Epitope Code, WT Epitope Sequence, B.1.1.7 (UK Variant), B.1.351 (South African Variant), P.1 (Brazilian Variant), B.1.617 (Indian Variant), Protein, Protein Region, Amino Acid, Network Score. Please contact Anusha Nathan at [e-mail] with questions.题为《基于结构指导的SARS-CoV-2变异株及沙贝病毒（Sarbecovirus）T细胞疫苗设计》的论文补充表格S3与S4。表格S3：经HLA（人类白细胞抗原）I类-肽稳定性实验检测的SARS-CoV-2表位列表。每一行对应一个高度网络化的SARS-CoV-2表位，列字段依次为：HLA、肽段编号、表位编码、表位序列、基因、氨基酸位点、蛋白质、蛋白质区域、网络评分、NetMHC结合评分、HLA稳定性、50%实验结合阳性判定（YES/NO）。表格S4：与图3相关的B.1.117、B.1.351、P.1及B.1.617变异株中可稳定HLA的高度网络化SARS-CoV-2表位序列。祖先毒株的突变以粗体标注。每一行对应一个高度网络化的SARS-CoV-2表位，列字段依次为：表位编码、野生型表位序列、B.1.1.7（英国变异株）、B.1.351（南非变异株）、P.1（巴西变异株）、B.1.617（印度变异株）、蛋白质、蛋白质区域、氨基酸位点、网络评分。如有疑问，请联系Anusha Nathan，邮箱地址为[e-mail]。