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High resolution chemical-genomics identifies targets for synergistic antibiotics with aztreonam

ChEBI2024-07-06 更新2026-07-12 收录

抗生素协同作用

化学基因组学药物筛选

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-11576 数据链接链接失效反馈

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资源简介：

High resolution chemical-genomics identifies targets for synergistic antibiotics with aztreonam

应用场景：

创建时间：

2024-07-06

抗生素协同作用

细菌耐药性

Introduction: Community-acquired urinary tract infections (UTIs) caused by extended spectrum beta-lactamase (ESBL)-producing Escherichia coli have limited oral therapeutic options and pose significant

DataCite Commons2022-06-07 更新100

Inhibitors that block initiation of wall teichoic acid biosynthesis sensitize methicillin-resistant Staphylococcus aureus to beta-lactams

细菌耐药性机制

抗生素协同作用

Methicillin resistance in Staphylococcus aureus depends on the production of mecA, which encodes penicillin-binding protein 2A (PBP2A), an acquired peptidoglycan transpeptidase with reduced susceptibi

NIAID Data Ecosystem20

Fosfomycin and amikacin show a highly synergistic interaction against resistant Escherichia coli

抗生素协同作用

大肠杆菌耐药性

Fosfomycin and amikacin show a highly synergistic interaction against resistant Escherichia coli

NIAID Data Ecosystem00

Prediction of Antibiotic Interactions Using Descriptors Derived from Molecular Structure

抗生素协同作用

药物组合计算筛选

Combination antibiotic therapies are clinically important in the fight against bacterial infections. However, the search space of drug combinations is large, making the identification of effective com

NIAID Data Ecosystem50

Membrane-active macromolecules kill antibiotic-tolerant bacteria and potentiate antibiotics towards Gram-negative bacteria

革兰氏阴性菌抗菌

抗生素协同作用

Chronic bacterial biofilms place a massive burden on healthcare due to the presence of antibiotic-tolerant dormant bacteria. Some of the conventional antibiotics such as erythromycin, vancomycin, line

Figshare2017-08-25 更新10

High resolution chemical-genomics identifies targets for synergistic antibiotics with aztreonam

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