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UPF1 knockdown in IPSC-derived cortical neurons

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NIAID Data Ecosystem2026-05-02 收录
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UPF1 is a key regulator of the nonsense-mediated decay (NMD) RNA degradation/quality control pathway. In this study, UPF1 knockdown was performed in IPSC-derived cortical-like neurons (NGN2) to characterise the transcriptome changes upon loss of UPF1 and NMD activity short-read bulk RNA-sequencing of IPSC-derived cortical neurons with and without UPF1 knockdown

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2025-08-01
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