Targeting androgen receptor phase separation to overcome antiandrogen resistance mediated by "pharmacological condensates"
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE185223
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资源简介：
Analyze the transcriptomic changes of LNCaP upon DMSO, DHT, Enzalutamide(ENZ), ET516 treatment. The DHT treatment induced robust androgen receptor (AR) signaling up-regulation, wheras ENZ and ET516 can significantly restore DHT-induced AR signaling changes. LNCaP cells were treated with 10 μM ET516/ENZ/DMSO (DHT was added 2 hours after the compound) for 12 hours. Subsequently RNA were extracted and sequencing libraries were prepared for high thourghput sequencing.
创建时间：
2021-10-05
